Research Associate

Seattle, WA

Posted: 07/29/2022 Job Number: 21305057

Job Description

RESEARCH ASSOCIATE
SEATTLE, WA
Project Description:
  • We are seeking an enthusiastic, self-driven individual to join the Gene Delivery Process & Analytical Development team and support the development of next-generation technologies to enable non-viral delivery for our cell therapy processes.
  • This Research Associate will support execution of analytical methods for nanoparticle characterization, as well as scale-up activities for nanoparticle formulations.
  • Design and execute fit-for-purpose analytical methods to characterize nanoparticle formulations.
  • Design and execute experiments to support downstream purification scale-up activities for nanoparticle formulations (i.E., liposomes, LNPs).
  • Perform data analysis, interpretation, and presentation to the team and relevant stakeholders.
  • Maintain accurate and detailed electronic laboratory notebook (ELN) and documentation of experimental results.
  • Author technical documents including protocols, reports, and contribute to regulatory documents.

Required Skills:
  • Bachelors (BS) or Masters (MS) Degree in Chemistry, Chemical Engineering, Bioengineering, Biochemistry, or related discipline.
  • 0-2 (MS) or 2+ (B.S.) years hands-on lab experience.
  • Familiarity in separation techniques (HPLC/UPLC, FFF, SEC), electrophoresis techniques (CE, gel electrophoresis), and nanoparticle physicochemical characterization (UV-Vis, DLS, cryo-EM, nucleic acid quantification, fluorescence plate reader assays like Ribogreen, etc.).
  • Ability to communicate clearly and concisely through oral presentation and technical writing.
  • Independently motivated with ability to multi-task and problem-solve.
  • Familiarity with lipid-based nanoparticle formulation generation and purification with microfluidic mixing instrumentation, spin-filtration, TFF, sterile filtration, and aseptic processing.
  • Familiarity with aseptic mammalian cell culture (preferably with primary cells).
  • Experience and working knowledge of concepts like statistical analysis and Design-of-Experiments (DOE).

This 12+ month position starts ASAP.

Please E-MAIL your resume (attachment to email) with rate and availability to Vic: vic@alphaconsulting.Com

ALPHA'S REQUIREMENT #22-02299
MUST BE ELIGIBLE TO WORK IN THE U.S. AS AN HOURLY W2 EMPLOYEE

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Vic Buch

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