Senior Research Associate

San Diego, CA

Posted: 06/21/2022 Job Number: 20827686

Job Description

100% Onsite.

Project Description:
This Senior Research Associate /Senior Associate Scientist will join in the Translational Development team in Oncogenesis Thematic Research Center (TRC) located in San Diego, California.
  • The incumbent will be responsible for addressing questions of drug scheduling, supporting patient selection hypothesis, and developing clinical assays using current techniques and primarily in vitro and ex vivo methods; and is responsible for experiment design, execution, and data analysis and report for well-defined projects.
  • The position will require handling and compound treatment of human tissues including whole blood, PBMC, bone marrow aspirates, tumor cell lines and primary tumors.
  • The incumbent will be expected to maintain an electronic lab notebook and organize results into reports or presentations.
  • Independently execute defined experiments, data analysis and data QC.
  • Design and conduct relevant molecular and cell-based assays to support MOA and translational research.
  • Analyze and present data in an organized and timely manner.
  • Thoughtful review of data and help plan next steps.
  • Work at the bench to design and execute established and novel molecular and cell-based assays for translational research.
  • Perform cell biology and molecular biology including primary and tumor cell culture, lentiviral transductions, RNA and protein preparation from cells and tissues, qRT-PCR, western blotting, and ELISA. Some training may be provided.
  • Hands on experience in working with CRISPR, siRNA and shRNA is a plus. Training will be provided.
  • May involve handling and processing patient derived tissues and blood samples.
  • Collaborate effectively and cultivate positive and productive relationships with colleagues.
  • Participate in maintenance of routine laboratory instrumentation and supplies.
  • Adherence to laboratory safety policies and practices.

Required Skills:
  • Have a Bachelor's degree in a scientific discipline with at least 3 years work experience.
  • Proven technical and scientific track record and experience working in a multi-disciplinary team environment.
  • Demonstrated proficiency in various molecular and cellular technologies including, but not limited to, sterile cell culture, cell-based assays (CTG, apoptosis), and molecular biology techniques (Protein, DNA and RNA isolations, Western blot, ELISA, qRT-PCR).
  • Proficiency with multi-color flow cytometry techniques and analysis.
  • Broad understanding of molecular cell biology, immunology, and oncology, with strong expertise in cell-based assay development and biomarker discovery.
  • Experience with high-throughput drug screening is a plus.
  • Skilled in Microsoft Office Suite, GraphPad Prism, FlowJo.
  • Possess trouble shooting and problem-solving skills to resolve technical questions in a multi-disciplinary environment.
  • Strong communication, writing and record keeping, and presentation skills.
  • Possess excellent communication, collaboration and organizational skills and attention to detail.
  • Ability to work in a fast-paced environment; flexibility to adapt to changes with a positive attitude.

This 12+ month position starts ASAP.

Please E-MAIL your resume (attachment to email) with rate and availability to Kevin: kevin@alphaconsulting.Com


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Kevin Anderson

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