San Diego,
CA
US
Posted: 06/21/2022
2022-06-21
2022-09-10
Job Number: 20827686
Job Description
SENIOR RESEARCH ASSOCIATE
SAN DIEGO, CA
100% Onsite.
Project Description:
This Senior Research Associate /Senior Associate Scientist will join in the Translational Development team in Oncogenesis Thematic Research Center (TRC) located in San Diego, California.
- The incumbent will be responsible for addressing questions of drug scheduling, supporting patient selection hypothesis, and developing clinical assays using current techniques and primarily in vitro and ex vivo methods; and is responsible for experiment design, execution, and data analysis and report for well-defined projects.
- The position will require handling and compound treatment of human tissues including whole blood, PBMC, bone marrow aspirates, tumor cell lines and primary tumors.
- The incumbent will be expected to maintain an electronic lab notebook and organize results into reports or presentations.
- Independently execute defined experiments, data analysis and data QC.
- Design and conduct relevant molecular and cell-based assays to support MOA and translational research.
- Analyze and present data in an organized and timely manner.
- Thoughtful review of data and help plan next steps.
- Work at the bench to design and execute established and novel molecular and cell-based assays for translational research.
- Perform cell biology and molecular biology including primary and tumor cell culture, lentiviral transductions, RNA and protein preparation from cells and tissues, qRT-PCR, western blotting, and ELISA. Some training may be provided.
- Hands on experience in working with CRISPR, siRNA and shRNA is a plus. Training will be provided.
- May involve handling and processing patient derived tissues and blood samples.
- Collaborate effectively and cultivate positive and productive relationships with colleagues.
- Participate in maintenance of routine laboratory instrumentation and supplies.
- Adherence to laboratory safety policies and practices.
Required Skills:
- Have a Bachelor's degree in a scientific discipline with at least 3 years work experience.
- Proven technical and scientific track record and experience working in a multi-disciplinary team environment.
- Demonstrated proficiency in various molecular and cellular technologies including, but not limited to, sterile cell culture, cell-based assays (CTG, apoptosis), and molecular biology techniques (Protein, DNA and RNA isolations, Western blot, ELISA, qRT-PCR).
- Proficiency with multi-color flow cytometry techniques and analysis.
- Broad understanding of molecular cell biology, immunology, and oncology, with strong expertise in cell-based assay development and biomarker discovery.
- Experience with high-throughput drug screening is a plus.
- Skilled in Microsoft Office Suite, GraphPad Prism, FlowJo.
- Possess trouble shooting and problem-solving skills to resolve technical questions in a multi-disciplinary environment.
- Strong communication, writing and record keeping, and presentation skills.
- Possess excellent communication, collaboration and organizational skills and attention to detail.
- Ability to work in a fast-paced environment; flexibility to adapt to changes with a positive attitude.
This 12+ month position starts ASAP.
Please E-MAIL your resume (attachment to email) with rate and availability to Kevin: kevin@alphaconsulting.Com
ALPHA'S REQUIREMENT #22-01928
MUST BE ELIGIBLE TO WORK IN THE U.S. AS AN HOURLY W2 EMPLOYEE
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