San Diego,
CA
92121
US
Posted: 08/22/2023
2023-08-22
2023-10-31
Job Number: 24792593
Job Description
RESEARCH SCIENTIST
SAN DIEGO, CA
Location: San Diego, CA.
100% Onsite.
TOP SKILLS:
- Ph.D. In cell biology, immunology, molecular biology, oncology, or equivalent field.
- Knowledge and experience in using multi-parameter flow cytometry.
- Hands-on experience with mammalian cell culture, molecular and cellular technologies (e.G., CRISPR/Cas9 knock-in/out, lentiviral transduction, western blotting, quantitative PCR,) and functional assays (e.G., proliferation, apoptosis, cell cycle) is essential.
- Experience in utilizing platforms including IncuCyte, JESS, Flow based cell sorter, ELISA, and MSD in the context of oncology-based drug discovery is a plus.
The pay ranges between $53.12 to $55.00 per hour.
Project Description:
- Utilize and develop multiple disease models to design target validation studies and relevant assays in support of SAR, mechanism of action, mechanisms of resistance, biomarker selection, and disease positioning.
- Develop and implement cell-based assays to address both tumor intrinsic cellular biology and immune-based mechanisms of action for potential drug candidates .
- Design and conduct essential mechanistic experiments in cell biology, cellular biochemistry, molecular biology, and assay development .
- Accurately maintain written reports and present results in an organized and timely manner.
- Communicate effectively, foster teamwork, and contribute to collaborative efforts.
- Strong commitment to quality and demonstrate adaptability.
Required Skills:
- Ph.D. In cell biology, immunology, molecular biology, or equivalent field with 0-2 years of post-doc or industry experience, or M.S. Degree with 3+ years of experience, or Bachelor's degree with 5+ years of experience in the biopharmaceutical industry developing and optimizing cell-based assays, preferably in Oncology .
- Strong background and experience in cancer research with training in molecular and cell biology .
- Extensive experience using multi-parameter flow cytometry in the context of primary immune cell isolation and characterization is required.
- Extensive hands-on experience with mammalian cell culture, molecular and cellular technologies (e.G., CRISPR/Cas9 knock-in/out, lentiviral transduction, western blotting, quantitative PCR,) and functional assays (e.G., proliferation, apoptosis, cell cycle) is essential .
- Strong record of high-impact and rigorous science though publication history.
- Proficiency in scientific data analysis programs including GraphPad Prism, FlowJo, Microsoft Excel/Powerpoint, is required .
- Capability to deliver high quality data in an organized and timely manner .
- Ability to work in a fast-paced dynamic team environment, flexibility to adapt to changes with a positive attitude and independently collaborate across teams, requiring excellent communication skills, both written and verbal, with strong interpersonal skills.
- Experience in utilizing platforms including IncuCyte, JESS, Flow based cell sorter, ELISA, and MSD in the context of oncology-based drug discovery is a plus.
This 12+month position starts ASAP.
Please E-MAIL your resume (attachment to email) with rate and availability to Bridget: bridget@alphaconsulting.Com
ALPHA'S REQUIREMENT #23-01422
MUST BE ELIGIBLE TO WORK IN THE U.S. AS AN HOURLY W2 EMPLOYEE
#LI-CK1
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